Driven with purpose to conduct clinical research impacting human health and public policy, our neuroscience team has contributed to the testing of innovative therapeutic solutions for decades. Emmes collaborates with a diverse client base of public and private sector organizations to enhance clinical practice and treatments for patients with neurological and psychiatric disorders. Our broad experience includes expertise in epilepsy, traumatic brain injury, autism, stroke, Alzheimer’s disease, schizophrenia, major depression and substance use.
To help advance your neuroscience research program, Emmes offers Phase I-IV clinical trial research services, from protocol development to regulatory submissions and publications. Our global monitoring capability across North America, Europe, and Asia ensures you can recruit the sites and patients necessary to complete your studies. To gain the insights required from your clinical trial, our team of experienced biostatisticians and clinicians employ validated neuropsychological and quality of life (QOL) assessments in your study design.
Neurology clinical trial protocols often require complex testing involving a variety of technologies. Emmes can help you optimize the collection, processing, and analysis of data collected from sites and patients across a variety of neurological diagnostic tools (e.g.,CT, structural MRI, fMRI, MR spectroscopy, EEG, diffusion tensor imaging) using our Advantage eClinical suite of clinical technologies.
To achieve your objectives of maximizing site and patient-level data, we provide electronic data capture of CRFs, patient reported outcomes and diaries, as well as data from phone apps, wearables, and other digital technologies.
Emmes is a different kind of CRO. Beyond clinical trial management services our neuroscience team also offers complex data warehousing and management solutions for biorepositories and clinical trials with multi-modal neuroimaging protocols. We currently serve as the data coordinating center for the National NeuroAIDS Tissue Consortium (NNTC), sponsored by the National Institute of Mental Health and the National Institute of Neurological Disorders and Stroke.
Our role in the consortium is to make tissue samples and data easily collectible, traceable, and accessible to researchers through the NNTC website (managed by Emmes). We also conduct a battery of ante and post-mortem tests on HIV/AIDS patients as well as provide data warehousing services for the program. To date, the NNTC effort has generated over 500 publications that advance the understanding of neurological and psychological disorders of HIV/AIDS patients.
The “different kind of CRO” story does not end there. It extends to supporting clinical trials testing therapeutics for mild traumatic brain injury, PTSD, stroke and rare diseases. We are also on the cutting edge of clinical research involving the use of psychedelic substances, such as psilocybin, to treat major depressive disorder andalcoholism. On your behalf, we can apply our niche experience in managing trials involving Schedule I drugs, easing the regulatory and logistical burdens of developing such products.Contact Us
Advancing Clinical Research Through Standardization
In an age of “big data” having access to standardized research study data opens up a world of possibilities. One can imagine endless ways to apply such data to improve the public health and scientific research. But how do we get there?
Since 2012 Emmes has served as the Center for Clinical Research Resources supporting the Common Data Elements (CDEs) program sponsored by the National Institute of Neurological Disorders and Stroke (NINDS). The purpose of this program “is to standardize the collection of investigational data to facilitate comparison of results across studies and more effectively aggregate information into significant metadata results.” A key focus of the project is to create common definitions and metadata which enable data sharing among researchers involved in neurological disorders.
Emmes helps NINDS achieve the program’s mission by managing the process and work groups to establish CDEs. We also develop, manage and maintain the content of the NINDS CDE website and database. Thousands of researchers worldwide access the site for information on neurological conditions including general, neuromuscular, stroke, and traumatic brain injury disorders. Today the number of CDEs in the NINDS’ program has grown to 18,000 across 24 neurological disorders, but there is still much to do. Contact us to learn more and how you can participate.