National Institute on Drug Abuse Clinical Trial Network Clinical Coordinating Center (NIDA CTN CCC)

Go back to Experience
Coordinating Center
Emmes U.S.
Project Status
Active
Project Lifespan
03/31/2005
Objective

To date, the efficacy of new treatments for drug addiction has been demonstrated primarily in specialized research settings, with somewhat restricted patient populations. To address this problem, the National Institute on Drug Abuse (NIDA) has established the National Drug Abuse Treatment (NDAT) Clinical Trials Network (CTN).
The mission of the CTN is to forge partnerships to improve the quality of drug abuse treatment nationwide. The objective of the CTN is twofold:

  • Conduct studies of behavioral, pharmacological, and integrated behavioral and pharmacological treatment interventions of therapeutic effect in rigorous, multi-site clinical trials to determine effectiveness across a broad range of community-based treatment settings and diversified study participant populations;
  • Transfer the research results to physicians, providers, and their patients to improve the quality of drug abuse treatment throughout the country using science as the vehicle. EMMES supports NIDA as the Clinical Coordinating Center (CCC) providing resources to support the CTN in its general operations and the conduct of the multi-site clinical trials. The major responsibilities include:
  • Providing protocol development and implementation support
  • Conducting quality assurance monitoring visits
  • Providing regulatory support
  • Reviewing and reporting SAEs
  • Training CTN members associated with various nodes and protocols
  • Providing pharmaceutical services
  • Managing pharmaceutical and laboratory services and supply logistics
    • Population

    Participants with substance abuse enroll in behavioral, pharmacological, and integrated treatment intervention studies conducted at some of the 240 Community-based Treatment Programs (CTPs) associated with 16 regional nodes across the United States.

    Centers

    The CTN consists of 13 university centers (Nodes) that are associated with approximately 240 community treatment programs (CTPs).

    Additional Information

    Active clinical trials:

  • HIV Rapid Testing and Counseling in Drug Abuse Treatment Programs in the U.S.
  • Methamphetamine abuse
  • Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvement
  • Prescription Opioid Addiction Treatment Study (POATS)
  • Starting Treatment with Agonist Replacement Therapies (START)
    Five new protocols are currently under development. More information will be posted as information becomes available.
    • Products
    Regulatory Tracking System
    Services
    Medical Monitoring
    Protocol Monitoring
    Regulatory Affairs
    Study Design/Protocol Development
    Training and Certification
    Substance Use