Building quality of life assessment into cancer treatment studies.
Year of Publication
Gotay, C C; Korn, E L; McCabe, M S; Moore, T D; Cheson, B D
Oncology (Williston Park)
25-8; discussion 30-2, 37
Clinical Trials as Topic; Humans; Neoplasms; quality of life
Quality of life is increasingly recognized as an important outcome of cancer treatment. However, quality of life research poses considerable problems in design and implementation. This article provides guidelines for the preparation of phase III therapeutic protocols that include quality of life assessment. The guidelines emphasize the distinct requirements of quality of life research and provide specific recommendations for the questions that need to be addressed in protocol development.