Effect of Concomitant Antibiotic and Vaccine Administration on Serologic Responses to Rotavirus Vaccine.

Publication Type
Journal Article
Year of Publication
2020
Authors
Anderson, Evan J; Lopman, Benjamin; Yi, Jumi; Libster, Romina; Creech, C Buddy; El-Khorazaty, Jill; Baqar, Shahida; Yildirim, Inci; Kao, Carol; Rouphael, Nadine; Shane, Andi L; Edwards, Kathryn
Secondary
J Pediatric Infect Dis Soc
Volume
9
Pagination
479-482
Date Published
2020 Sep 17
Keywords
Administration, Oral; Anti-Bacterial Agents; Child; CRID; Female; Humans; Immunoglobulin A; Male; Rotavirus Infections; Rotavirus Vaccines
Abstract

Data from 1174 infants enrolled in a previous rotavirus vaccine study were analyzed to determine the effect of antibiotic exposure (from 14 days before to 7 days after vaccination) on rotavirus serum immunoglobulin A (IgA) responses. Serum IgA responses 1 month after the completion of vaccination were similar among antibiotic-exposed and nonexposed infants.