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Durability of mRNA-1273 vaccine-induced antibodies against SARS-CoV-2 variants.

2021 09 17

Journal Article

Authors:
Pegu, A.; O'Connell, S.E.; Schmidt, S.D.; O'Dell, S.; Talana, C.A.; Lai, L.; Albert, J.; Anderson, E.; Bennett, H.; Corbett, K.S.; Flach, B.; Jackson, L.; Leav, B.; Ledgerwood, J.E.; Luke, C.J.; Makowski, M.; Nason, M.C.; Roberts, P.C.; Roederer, M.; Rebolledo, P.A.; Rostad, C.A.; Rouphael, N.G.; Shi, W.; Wang, L.; Widge, A.T.; Yang, E.Sung; Beigel, J.H.; Graham, B.S.; Mascola, J.R.; Suthar, M.S.; McDermott, A.B.; Doria-Rose, N.A.; Arega, J.; Beigel, J.H.; Buchanan, W.; Elsafy, M.; Hoang, B.; Lampley, R.; Kolhekar, A.; Koo, H.; Luke, C.; Makhene, M.; Nayak, S.; Pikaart-Tautges, R.; Roberts, P.C.; Russell, J.; Sindall, E.; Albert, J.; Kunwar, P.; Makowski, M.; Anderson, E.J.; Bechnak, A.; Bower, M.; Camacho-Gonzalez, A.F.; Collins, M.; Drobeniuc, A.; Edara, V.Viswanadh; Edupuganti, S.; Floyd, K.; Gibson, T.; Ackerley, C.M.Grimsley; Johnson, B.; Kamidani, S.; Kao, C.; Kelley, C.; Lai, L.; Macenczak, H.; McCullough, M.Paine; Peters, E.; Phadke, V.K.; Rebolledo, P.A.; Rostad, C.A.; Rouphael, N.; Scherer, E.; Sherman, A.; Stephens, K.; Suthar, M.S.; Teherani, M.; Traenkner, J.; Winston, J.; Yildirim, I.; Barr, L.; Benoit, J.; Carste, B.; Choe, J.; Dunstan, M.; Erolin, R.; Ffitch, J.; Fields, C.; Jackson, L.A.; Kiniry, E.; Lasicka, S.; Lee, S.; Nguyen, M.; Pimienta, S.; Suyehira, J.; Witte, M.; Bennett, H.; Altaras, N.Emil; Carfi, A.; Hurley, M.; Leav, B.; Pajon, R.; Sun, W.; Zaks, T.; Coler, R.N.; Larsen, S.E.; Neuzil, K.M.; Lindesmith, L.C.; Martinez, D.R.; Munt, J.; Mallory, M.; Edwards, C.; Baric, R.S.; Berkowitz, N.M.; Boritz, E.A.; Carlton, K.; Corbett, K.S.; Costner, P.; Creanga, A.; Doria-Rose, N.A.; Douek, D.C.; Flach, B.; Gaudinski, M.; Gordon, I.; Graham, B.S.; Holman, L.S.; Ledgerwood, J.E.; Leung, K.; Lin, B.C.; Louder, M.K.; Mascola, J.R.; McDermott, A.B.; Morabito, K.M.; Novik, L.; O'Connell, S.; O'Dell, S.; Padilla, M.; Pegu, A.; Schmidt, S.D.; Shi, W.; Swanson, P.A.; Talana, C.A.; Wang, L.; Widge, A.T.; Yang, E.Sung; Zhang, Y.; Chappell, J.D.; Denison, M.R.; Hughes, T.; Lu, X.; Pruijssers, A.J.; Stevens, L.J.; Posavad, C.M.; Gale, M.; Menachery, V.; Shi, P.Y.

Secondary:
Science

Volume:
373

Pagination:
1372-1377

Issue:
6561

PMID:
34385356

URL:
https://pubmed.ncbi.nlm.nih.gov/34385356/

DOI:
10.1126/science.abj4176

Keywords:
Adolescent; Adult; Aged; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Cross Reactions; Humans; Immune Evasion; Immunization, Secondary; Immunogenicity, Vaccine; Middle Aged; SARS-CoV-2; Time Factors; Young Adult

Abstract:
[Figure: see text].

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