A two-sample test sensitive to crossing hazards in uncensored and singly censored data.
Stablein, D.M.; Koutrouvelis, I.A.
Antineoplastic Combined Chemotherapy Protocols; Biometry; Clinical Trials as Topic; Combined Modality Therapy; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Mathematics
Savage score statistics are employed to develop a test for comparing survival distributions with right-hand singly censored data. The procedure is motivated by the interest in developing a powerful method for determining differences when true survival distributions cross. Examination of small-sample characteristics under the null hypothesis indicate that asymptotic critical values yield a slightly conservative test. Power of the test compares favorably with other criteria, including the modified Smirnov procedure, particularly if there is a single crossing of the survival curves.