Timing and characteristics of multiple peritonitis episodes: a report of the National CAPD Registry.
1989 Jul
Journal Article
Authors:
Stablein, D.M.;
Nolph, K.D.;
Lindblad, A.S.
Secondary:
Am J Kidney Dis
Volume:
14
Pagination:
44-9
Issue:
1
PMID:
2741935
DOI:
10.1016/s0272-6386(89)80092-7
Keywords:
Adult; Aged; Bacteria; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; peritoneal dialysis; Peritoneal Dialysis, Continuous Ambulatory; peritonitis; Recurrence; Renal Dialysis; Risk Factors
Abstract:
Patterns of recurrent peritonitis episodes were examined in 6,335 new continuous ambulatory peritoneal dialysis (CAPD) patients entered into the National CAPD Registry. Forty-six percent of all peritonitis episodes were initial occurrences, with 8% of the patients reporting four or more episodes. The proportion of gram-positive and gram-negative infections was constant across episodes. In patients with multiple infections, negative organisms were found to have increased risk of recurring as gram-negative infection. A similar observation was made for fungal infections. Of patients with multiple peritonitis episodes, more than 40% of those who transferred to other maintenance renal replacement therapy identified peritonitis as the reason for transfer. A discrete time logistic model was used to estimate peritonitis risk in 4-month follow-up periods. Patients like those on the registry are estimated to have a 22% risk of developing peritonitis during any 4-month period. This risk was increased 4% for patients aged less than 21 years, 7% for nonwhite patients, and 19% in the period following a peritoneal infection.
