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Adjusting Moran's I for population density.

1995 Jan 15

Journal Article

Authors:
Oden, N.

Secondary:
Stat Med

Volume:
14

Pagination:
17-26

Issue:
1

PMID:
7701154

DOI:
10.1002/sim.4780140104

Keywords:
Analysis of Variance; Cluster Analysis; Georgia; Humans; Incidence; Lyme Disease; Models, Statistical; Population Density; Random Allocation; Risk Factors; Space-Time Clustering

Abstract:
I derive two new statistics, Ipop and Ipop*, that adjust Moran's I to study clustering of disease cases in areas (for example, counties) with different, known population densities. A simulation of Lyme disease in Georgia suggests that these new statistics can be more powerful than those currently in use. This is because they consider both spatial pattern and non-binomial variance in rates as evidence supporting disease clusters.

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