Agreement between time-domain and spectral-domain optical coherence tomography in the assessment of macular thickness in patients with idiopathic macular telangiectasia type 2.
2013
Journal Article
Authors:
Mathew, R.;
Sivaprasad, S.;
Florea, D.;
Leung, I.;
Sallo, F.;
Clemons, T.;
Bird, A.C.;
Peto, T.
Secondary:
Ophthalmologica
Volume:
230
Pagination:
144-50
Issue:
3
PMID:
23989133
Keywords:
Humans; Prospective Studies; Reproducibility of Results; retina; Retinal Telangiectasis; Time Factors; Tomography, Optical Coherence
Abstract:
PURPOSE: To estimate the conversion factors to transpose macular thickness measurements on time-domain (TD) to various spectral-domain (SD) optical coherence tomography (OCT) machines in patients with macular telangiectasia type 2a (MacTel).PROCEDURES: Macular scans on TD- and SD-OCT were performed on patients at the same visit. The retinal thickness values in various ETDRS subfields and macular volume were compared between different OCT machines.RESULTS: The macular thickness and volume were significantly greater (p < 0.0001, r = 0.678-0.822) on SD-OCT. The mean differences in macular thickness between TD Stratus and SD-OCT by Spectralis, Cirrus and Topcon were 62, 41 and 20 μm, respectively. The conversion factor of macular thickness from TD-OCT to Spectralis, Cirrus and Topcon were +65, +39 and +25 μm, respectively.CONCLUSION AND MESSAGE: The estimates of conversion of macular thickness from TD- to SD-OCT using simple mean differences between machines and those by linear regression were similar suggesting that the former may be used for the longitudinal follow-up of MacTel patients.
