Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.
2013 Feb
Journal Article
Authors:
Seña, A.C.;
Wolff, M.;
Behets, F.;
Van Damme, K.;
Martin, D.H.;
Leone, P.;
McNeil, L.;
Hook, E.W.
Secondary:
Clin Infect Dis
Volume:
56
Pagination:
420-2
Issue:
3
PMID:
23118269
Keywords:
Adolescent; Adult; Anti-Bacterial Agents; Female; Humans; Male; Middle Aged; Penicillin G Benzathine; Retreatment; Syphilis; Syphilis Serodiagnosis; Time Factors; Treatment Outcome; Young Adult
Abstract:
Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.
